注册 登录  
 加关注
   显示下一条  |  关闭
温馨提示!由于新浪微博认证机制调整,您的新浪微博帐号绑定已过期,请重新绑定!立即重新绑定新浪微博》  |  关闭

阳光勾勒微笑的博客

http://www.letaod.com/

 
 
 

日志

 
 

Day-Old Mice Grow Back New Heart Tissu..  

2011-06-30 21:26:00|  分类: 我的日记 |  标签: |举报 |字号 订阅

  下载LOFTER 我的照片书  |





Art Chimes | St. Louis, Missouri
 March 02, 2011

Photo: Science/AAAS
In contrast to the adult mouse heart that heals by scar formation, the newborn heart heals by complete regeneration within three weeks after injury.
When humans have a heart attack, heart muscles die after being cut off from their blood supply. But what if the heart could grow new muscle to replace the dead tissue?FIFA Officials Banned Over World Cup B.. - bosoudd - 未完的歌的博客3d眼镜 3D立体眼镜组合 3d立体眼镜套装 3d电影 升级镜片第6代 16.88元 Day-Old Mice Grow Back New Heart Tissu.. - bosoucc - 阳光勾勒微笑的博客


Some amphibians can regrow body parts, even entire limbs. But humans and other higher animals mostly lack that ability, called regeneration. There are exceptions. Liver tissue, for example, will regrow after part of the organ is removed in surgery. But that's not true with most other organs, including the heart.

In a new  at the University of Texas Southwestern Medical Center, researchers cut off a piece of the heart in tiny, day-old mice. Hesham Sadek explains the procedure.

"We cut off the tip until we see the chamber of the heart. And amazingly enough, the animals survive and they form a blood clot and they don't bleed to death. And within three weeks, that tip grows back."

Grows back as normal, functioning heart muscle, not just closed up with scar tissue.

The mice retain the ability to grow back functioning heart tissue only during their first week of life, and Sadek says it's important to identify exactly when the mouse stops being able to regenerate heart tissue, to see what other changes happen at that point "so we can identify potential factors that are either on or off at this window that we can reintroduce them or block them and have the heart regain this capacity again."

What is encouraging, Sadek says, is that the heart - or at least the mouse heart - is born with this ability to regenerate.

"We discovered that the heart can do this by itself," he says. "It just forgets how to do that or turns it off for some reason. And the question now is, can we remind the heart to do this again?"

And not just after a week or two - but decades later, when a person suffers a heart attack.

"If we can develop actual therapies from this model, the goal would be to convince the heart, instead of forming a scar, the heart now will basically just fill it back up with contractile cells, cells that will contract and pump blood, and the heart will regain its function again."
<div id="
  评论这张
 
阅读(2)| 评论(0)
推荐 转载

历史上的今天

评论

<#--最新日志,群博日志--> <#--推荐日志--> <#--引用记录--> <#--博主推荐--> <#--随机阅读--> <#--首页推荐--> <#--历史上的今天--> <#--被推荐日志--> <#--上一篇,下一篇--> <#-- 热度 --> <#-- 网易新闻广告 --> <#--右边模块结构--> <#--评论模块结构--> <#--引用模块结构--> <#--博主发起的投票-->
 
 
 
 
 
 
 
 
 
 
 
 
 
 

页脚

网易公司版权所有 ©1997-2018